SubtiBank SubtiBank
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2019-08-23 09:45:022019-08-23 09:43:35

Gene

Phenotypes of a mutant

a ''[[gene|cwlO]] [[gene|lytE]]'' mutant is not viable [Pubmed|17581128,22139507]

growth defect at high temperature [Pubmed|21541672]

inactivation of ''[[gene|lytE]]'' strongly restores beta-lactam resistance in a ''[[gene|sigM]]'' mutant by delaying cell lysis [Pubmed|22211522]

synthetically lethal with ''[[gene|ftsE]]'' and ''[[gene|ftsX]]'' mutation (due to a lack of autolysin activity) [Pubmed|23869552,23855774]

synthetically lethal with [[gene|sweC]] and [[gene|sweD]] [pubmed|31437162]

a ''[[gene|lytE]]'' mutation increases the cell separation defect of a ''[[gene|lytF]]'' mutant [Pubmed|23855774]

cells are thinner (reduced diameter) as compared to the wild type [Pubmed|23869552]

reduced colony size with accumulation of dead cells in the colonies [pubmed|29114240]

a ''[[gene|cwlO]] [[gene|lytE]]'' mutant is not viable [Pubmed|17581128,22139507]

growth defect at high temperature [Pubmed|21541672]

inactivation of ''[[gene|lytE]]'' strongly restores beta-lactam resistance in a ''[[gene|sigM]]'' mutant by delaying cell lysis [Pubmed|22211522]

a ''[[gene|lytE]]'' mutation is synthetically lethal with ''[[gene|ftsE]]'' and ''[[gene|ftsX]]'' mutation (due to a lack of autolysin activity) [Pubmed|23869552,23855774]

a ''[[gene|lytE]]'' mutation increases the cell separation defect of a ''[[gene|lytF]]'' mutant [Pubmed|23855774]

cells are thinner (reduced diameter) as compared to the wild type [Pubmed|23869552]

reduced colony size with accumulation of dead cells in the colonies [pubmed|29114240]

References

Original publications

21261835, 22211522, 16950129, 17581128, 14594841, 9457885, 9573210, 10322020, 24125693, 23199363, 20059685, 14651647, 23869552, 21541672, 22139507, 23855774, 27118079, 25760608, 29114240, 29458655, 29914988, 29458657, 29465029, 31437162

21261835, 22211522, 16950129, 17581128, 14594841, 9457885, 9573210, 10322020, 24125693, 23199363, 20059685, 14651647, 23869552, 21541672, 22139507, 23855774, 27118079, 25760608, 29114240, 29458655, 29914988, 29458657, 29465029